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  • Frontal
  • Podium Abstract

    Determining the Fundamental Building Blocks of the Apoptosis Pathway Across Multiple Cancers

    • Zach Abrams ;
    • Hetian Bai ;
    • Min Wang ;
    • Kevin Coombes

    Determining the Fundamental Building Blocks of the Apoptosis Pathway Across Multiple Cancers


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    Understanding Immune System Sex Differences Through the Transcriptome

    • Erika Bongen ;
    • PJ Utz ;
    • Purvesh Khatri

    Understanding Immune System Sex Differences Through the Transcriptome


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    Towards Patient-Driven Phenotyping and Similarity for Precision Medicine

    • Tiffany J. Callahan ;
    • Olivier Bodenreider ;
    • Michael G. Kahn

    Towards Patient-Driven Phenotyping and Similarity for Precision Medicine


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    Binding Structured Molecular Pathology Test Data with i2b2 Datasets – A preliminary evaluation of targeted treatment pathways in cancer patients

    • Walter S. Campbell ;
    • Aaron D. Bossler ;
    • James R. Campbell

    Binding Structured Molecular Pathology Test Data with i2b2 Datasets – A preliminary evaluation of targeted treatment pathways in cancer patients


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    Evaluation and Testing of Containerized I2B2 Deployment using Docker

    • Pralav Dessai ;
    • Kavishwar B. Wagholikar ;
    • Fernando J. Sanz-Vidorreta

    Evaluation and Testing of Containerized I2B2 Deployment using Docker


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    Open science integration for mechanistic disease discovery in Fanconi Anemia

    • Melissa A. Haendel ;
    • Christopher J. Mungall ;
    • Julie McMurry ;
    • Christopher G. Chute ;
    • Maureen Hoatlin

    Open science integration for mechanistic disease discovery in Fanconi Anemia


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    Patient-led deep phenotyping using a lay-friendly version of the Human Phenotype Ontology

    • Melissa A. Haendel ;
    • Nicole Vasilevsky ;
    • Catherine Brownstein ;
    • Ingrid Holm ;
    • Kayli Rageth ;
    • Peter Robinson ;
    • Sebastian Köhler

    Patient-led deep phenotyping using a lay-friendly version of the Human Phenotype Ontology


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    Multi-omics data integration strategy improves survival prognostication in renal cell carcinoma

    • Haruka Itakura ;
    • Olivier Gevaert

    Multi-omics data integration strategy improves survival prognostication in renal cell carcinoma


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    Speeding Genetic Discovery in Autism through the iHART Information Commons

    • Jae-Yoon Jung ;
    • Nate Stockham ;
    • Kelley Paskov ;
    • Anika Gupta ;
    • Min Woo Sun ;
    • Dennis Wall

    Speeding Genetic Discovery in Autism through the iHART Information Commons


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    Meta-Analysis of Vaginal Microbiome Data Provides New Insights into Preterm Birth

    • Idit Kosti ;
    • Svetlana Lyalina ;
    • Katherine S. Pollard ;
    • Atul Butte ;
    • Marina Sirota

    Meta-Analysis of Vaginal Microbiome Data Provides New Insights into Preterm Birth


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    Discovering Biomarkers associated with Type II Diabetes Mellitus using NHANES Databas

    • Ying Li ;
    • Hanying Yan ;
    • Xiaoyu Song

    Discovering Biomarkers associated with Type II Diabetes Mellitus using NHANES Databas


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    A Multi-Scale Modeling Approach to Identify Optical Pathway Gliomas and Autism Spectrum Disorder in Individuals with Neurofibromatosis Type 1 (NF1)

    • Matthew Lui ;
    • Aditi Gupta ;
    • Stephanie M. Morris ;
    • David H. Gutmann ;
    • Philip Payne

    A Multi-Scale Modeling Approach to Identify Optical Pathway Gliomas and Autism Spectrum Disorder in Individuals with Neurofibromatosis Type 1 (NF1)


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    Multiscale Profiling and Predictive Modeling of Responders and Non-Responders to Periodontal Therapies

    • Radha Nagarajan ;
    • Craig Miller ;
    • Jeffrey Ebersole

    Multiscale Profiling and Predictive Modeling of Responders and Non-Responders to Periodontal Therapies


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    Vanderbilt University Medical Center’s Drug Repurposing Program: Using Human Genetic Information to Find Effective and Affordable Therapies

    • Helen Naylor ;
    • Jana K. Shirey-Rice ;
    • Nicole M. Zaleski ;
    • Rebecca J. Jerome ;
    • Robert R. Lavieri ;
    • Ardina J. Pruijssers ;
    • Somsundaram N. Chettiar ;
    • Jill Pulley ;
    • Nunzia Giuse

    Vanderbilt University Medical Center’s Drug Repurposing Program: Using Human Genetic Information to Find Effective and Affordable Therapies


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    An automated guidelines-based approach for variants pathogenicity assessment

    • Giovanna Nicora ;
    • Ivan Limongelli ;
    • Patrick Gambelli ;
    • Mirella Memmi ;
    • Carlo Napolitano ;
    • Alberto L. Malovini ;
    • Andrea Mazzanti ;
    • Silvia Priori ;
    • Riccardo Bellazzi

    An automated guidelines-based approach for variants pathogenicity assessment


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    Tandem Rank-Goodness of Fit is a Feasible Measure to Guide Agnostic Metabolic Profile Selection in Automated Machine Learning Applications

    • Alena Orlenko ;
    • Jason H. Moore ;
    • Daniel J. Rader ;
    • Sony Tuteja ;
    • Matthew K. Breitenstein

    Tandem Rank-Goodness of Fit is a Feasible Measure to Guide Agnostic Metabolic Profile Selection in Automated Machine Learning Applications


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    Big data deep neural network to analyze adverse vaccine reactions

    • Ahmad P. Tafti ;
    • Mehdi Assefi ;
    • Eric R. LaRose ;
    • Jonathan C. Badger ;
    • Zhan Ye (Harold) ;
    • Neel Shimpi ;
    • Fereshteh S. Bashiri ;
    • Elham Sagheb ;
    • Huong McLean ;
    • Peggy L. Peissig ;
    • David Page

    Big data deep neural network to analyze adverse vaccine reactions


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    Computational Identification of Colorectal Adenoma-Related Genes Using Machine Learning and Network Analysis

    • Jie Ping ;
    • Xuemin Pan ;
    • Xiao Dong ;
    • Jing-Fang Wang

    Computational Identification of Colorectal Adenoma-Related Genes Using Machine Learning and Network Analysis


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    Expanding the Practice of Reproducible Research in Biomedical Informatics with StatTag and Microsoft Word

    • Luke V. Rasmussen ;
    • Abigail S. Baldridge ;
    • Eric Whitley ;
    • Leah J. Welty

    Expanding the Practice of Reproducible Research in Biomedical Informatics with StatTag and Microsoft Word


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    Integrative Analysis of Immune Repertoire & Differential Gene Expression from RNA-seq in Kidney Organ Transplants

    • Akshay Ravoor ;
    • Silvia Pineda ;
    • Tara Sigdel ;
    • Dmitry Rychkov ;
    • Oriol Bestard ;
    • Minnie Sarwal ;
    • Marina Sirota

    Integrative Analysis of Immune Repertoire & Differential Gene Expression from RNA-seq in Kidney Organ Transplants


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    VenomSeq–A platform for drug discovery from animal venoms using differential gene expression

    • Joseph D. Romano ;
    • Hai Li ;
    • Ronald Realubit ;
    • Charles Karan ;
    • Nicholas P. Tatonetti

    VenomSeq–A platform for drug discovery from animal venoms using differential gene expression


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    Incorporating Observation Error in the Geospatial Assignment of Taxa for Virus Phylogeography

    • Matthew Scotch ;
    • Tasnia Tahsin ;
    • Davy Weissenbacher ;
    • Karen O'Connor ;
    • Arjun Magge ;
    • Marc A. Suchard ;
    • Graciela Gonzalez

    Incorporating Observation Error in the Geospatial Assignment of Taxa for Virus Phylogeography


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    Creating a Multi-Organism Disease Model Resource at RGD

    • Mary Shimoyama ;
    • Stanley J. Laulederkind ;
    • Jeff De Pons ;
    • Elizabeth Bolton ;
    • Omid Ghiasvand ;
    • G. T. Hayman ;
    • Hoffman Matthew ;
    • Jennifer R. Smith ;
    • Jyothi Thota ;
    • Marek Tutaj ;
    • Monika Tutaj ;
    • Yiqing Zhao ;
    • Melinda R. Dwinell

    Creating a Multi-Organism Disease Model Resource at RGD


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    Open Access Economics in the Big Genomics Era

    • Nate Stockham

    Open Access Economics in the Big Genomics Era


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    Rapid Mobilized Video Phenotyping for Autism Diagnosis

    • Qandeel Tariq ;
    • Jena Daniels ;
    • Michael Du ;
    • Jessey Schwartz ;
    • Dennis Wall

    Rapid Mobilized Video Phenotyping for Autism Diagnosis


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    Heart Rate Variability Response to Vasopressor Intervention in Critically Ill Patients

    • Victoria J. Tolls ;
    • Evelyn Morin ;
    • Karen Rudie ;
    • Andrew Seely ;
    • Usman Raza ;
    • David M. Maslove

    Heart Rate Variability Response to Vasopressor Intervention in Critically Ill Patients


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    Development of MRI-based Radiomics Signature for Predicting Molecular Subtypes in Medulloblastoma

    • Zichen Wang ;
    • Mu Zhou ;
    • Eric Tranvinh ;
    • Bryan Lanzman ;
    • Katie Shpanskaya ;
    • Tina Poussaint ;
    • Michael Iv ;
    • Kristen W. Yeom ;
    • Olivier Gevaert

    Development of MRI-based Radiomics Signature for Predicting Molecular Subtypes in Medulloblastoma


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    Generative Adversarial Networks: Evaluating Drug Effect in Synthetic Time Series Generated from EHR Data

    • Alexandre Yahi ;
    • Rami Vanguri ;
    • Noemie Elhadad ;
    • Nicholas P. Tatonetti

    Generative Adversarial Networks: Evaluating Drug Effect in Synthetic Time Series Generated from EHR Data


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    Deciphering the Molecular Basis of Lung Adenocarcinoma Dedifferentiation and Prognosis by Integrating Omics and Histopathology

    • Kun-Hsing Yu ;
    • Gerald Berry ;
    • Daniel Rubin ;
    • Christopher Re ;
    • Russ B. Altman ;
    • Michael Snyder

    Deciphering the Molecular Basis of Lung Adenocarcinoma Dedifferentiation and Prognosis by Integrating Omics and Histopathology


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    Molecular Modeling and Simulations to Discern the Consequences of Rare and Polymorphic STING Variants

    • Michael T. Zimmermann ;
    • Emily Voigt ;
    • Iana Haralambieva ;
    • Inna Ovsyannikova ;
    • Schaid Daniel ;
    • Gregory Poland ;
    • Richard Kennedy

    Molecular Modeling and Simulations to Discern the Consequences of Rare and Polymorphic STING Variants


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